* Generic Name: celecoxib
* Brand Name: Celebrex
* What is celecoxib (CeleBREX)?
* What are the possible side effects of celecoxib (CeleBREX)?
* What is the most important information I should know about
celecoxib (CeleBREX)?
* What should I discuss with my healthcare provider before taking
celecoxib (CeleBREX)?
* How should I take celecoxib (CeleBREX)?
* What happens if I miss a dose (CeleBREX)?
* What happens if I overdose (CeleBREX)?
* What should I avoid while taking celecoxib (CeleBREX)?
* What other drugs will affect celecoxib (CeleBREX)?
* Where can I get more information (CeleBREX)?
What is celecoxib (CeleBREX)?
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID).
Celecoxib works by reducing hormones that cause inflammation and pain
in the body.
Celecoxib is used to treat pain or inflammation caused by many
conditions such as arthritis, ankylosing spondylitis, and
menstrual pain. Celecoxib is used to treat juvenile rheumatoid
arthritis in children who are at least 2 years old. Celecoxib is also
used in the treatment of hereditary polyps in the colon.
Celecoxib may also be used for purposes not listed in this medication
guide.
What are the possible side effects of celecoxib (CeleBREX)?
Get emergency medical help if you have signs of an allergic reaction:
sneezing, runny or stuffy nose; wheezing or trouble
breathing; hives; swelling of your face, lips, tongue, or throat.
Get emergency medical help if you have signs of a heart attack or
stroke: chest pain spreading to your jaw or shoulder, sudden
numbness or weakness on one side of the body, slurred speech,
feeling short of breath.
Stop using celecoxib and call your doctor at once if you have:
* the first sign of any skin rash, no matter how mild;
* shortness of breath (even with mild exertion);
* swelling or rapid weight gain;
* signs of stomach bleeding--bloody or tarry stools, coughing up
blood or vomit that looks like coffee grounds;
* liver problems--nausea, upper stomach pain, itching, tired feeling,
flu-like symptoms, loss of appetite, dark urine,
clay-colored stools, jaundice (yellowing of the skin or eyes);
* kidney problems--little or no urinating, painful or difficult
urination, swelling in your feet or ankles, feeling tired or short
of breath;
* low red blood cells (anemia)--pale skin, feeling light-headed
or short of breath, rapid heart rate, trouble concentrating; or
* severe skin reaction--fever, sore throat, swelling in your face
or tongue, burning in your eyes, skin pain followed by a red or
purple skin rash that spreads (especially in the face or upper
body) and causes blistering and peeling.
Common side effects may include:
* stomach pain, indigestion, gas, diarrhea;
* swelling in your hands or feet;
* dizziness;
* rash; or
* cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about celecoxib
(CeleBREX)?
Celecoxib can increase your risk of fatal heart attack or stroke,
especially if you use it long term or take high doses, or if you have
heart disease. Do not use this medicine just before or after heart
bypass surgery (coronary artery bypass graft, or CABG).
Celecoxib may also cause stomach or intestinal bleeding, which can be
fatal. These conditions can occur without warning while you are using
celecoxib, especially in older adults. You should not take this
medicine if you already have bleeding in your stomach or intestines.
Celebrex Patient Information including How Should I Take
Rheumatoid Arthritis Symptoms and Treatment
Rheumatoid Arthritis Slideshow
RxList
Take the RA Quiz
Rheumatoid Arthritis Exercises:Joint-Friendly Fitness Routines
Joint-Friendly Exercises Slideshow
What should I discuss with my healthcare provider before taking celecoxib
(CeleBREX)?
Celecoxib can increase your risk of fatal heart attack or stroke,
especially if you use it long term or take high doses, or if you have
heart disease. Even people without heart disease or risk factors could
have a stroke or heart attack while taking this medicine.
Do not use this medicine just before or after heart bypass surgery
(coronary artery bypass graft, or CABG).
Celecoxib may also cause stomach or intestinal bleeding, which can be
fatal. These conditions can occur without warning while you are using
celecoxib, especially in older adults.
You should not use celecoxib if you are allergic to it, or if you have:
* bleeding in your stomach or intestines;
* an allergy to sulfa drugs; or
* a history of asthma attack or severe allergic reaction after
taking aspirin or an NSAID.
To make sure celecoxib is safe for you, tell your doctor if you have:
* heart disease, high blood pressure, high cholesterol,
diabetes, or if you smoke;
* a history of heart attack, stroke, or blood clot;
* a history of stomach ulcers or bleeding;
* asthma;
* liver or kidney disease; or
* fluid retention.
Taking celecoxib during the last 3 months of pregnancy may harm the
unborn baby. Tell your doctor if you are pregnant or plan to become
pregnant while using celecoxib.
Celecoxib can pass into breast milk and may harm a nursing baby. Tell
your doctor if you are breast-feeding a baby.
Celecoxib is not approved for use by anyone younger than 2 years old.
How should I take celecoxib (CeleBREX)?
Follow all directions on your prescription label. Do not take this
medicine in larger amounts or for longer than recommended. Use the
lowest dose that is effective in treating your condition.
You may take celecoxib with or without food.
Take with food if celecoxib upsets your stomach.
To make swallowing easier, you may open the celecoxib capsule and
sprinkle the medicine into a spoonful of applesauce. Swallow right away
without chewing. Discard the empty capsule. If you do not take the
mixture right away, keep it in the refrigerator and take it within 6
hours.
If you use this medicine long-term, you may need frequent medical
tests.
Store at room temperature away from moisture and heat.
Read all patient information, medication guides, and instruction sheets
provided to you. Ask your doctor or pharmacist if you have any
questions.
Celebrex Patient Information including If I Miss a Dose
Rheumatoid Arthritis Symptoms and Treatment
Rheumatoid Arthritis Slideshow
RxList
Take the RA Quiz
Rheumatoid Arthritis Exercises:Joint-Friendly Fitness Routines
Joint-Friendly Exercises Slideshow
What happens if I miss a dose (CeleBREX)?
Since celecoxib is sometimes used when needed, you may not be on a
dosing schedule. If you are on a schedule, use the missed dose as soon
as you remember. Skip the missed dose if it is almost time for your
next scheduled dose. Do not use extra medicine to make up the missed
dose.
What happens if I overdose (CeleBREX)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking celecoxib (CeleBREX)?
Avoid drinking alcohol. It may increase your risk of stomach bleeding.
Avoid taking aspirin or other NSAIDs while you are taking
celecoxib.
Ask a doctor or pharmacist before using any cold, allergy, or pain
medication. Many medicines available over the counter contain aspirin
or other medicines similar to celecoxib. Taking certain products
together can cause you to get too much of this type of medication.
Check the label to see if a medicine contains aspirin, ibuprofen,
ketoprofen, or naproxen.
What other drugs will affect celecoxib (CeleBREX)?
Ask your doctor before using celecoxib if you take an antidepressant
such as citalopram, escitalopram, fluoxetine (Prozac),
fluvoxamine, paroxetine, sertraline (Zoloft),
trazodone, or vilazodone. Taking any of these medicines with an
NSAID may cause you to bruise or bleed easily.
Tell your doctor about all your current medicines and any you start or
stop using, especially:
* fluconazole;
* lithium;
* a blood thinner (warfarin, Coumadin, Jantoven);
* heart or blood pressure medication, including a diuretic or
"water pill"; or
* steroid medicine (such as prednisone).
This list is not complete. Other drugs may interact with celecoxib,
including prescription and over-the-counter medicines, vitamins, and
herbal products. Not all possible interactions are listed in this
medication guide.
Where can I get more information (CeleBREX)?
Your pharmacist can provide more information about celecoxib.
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