* Generic Name: doxepin
* Brand Name: Sinequan
* What is doxepin (Sinequan) (Adapin, SINEquan)?
* What are the possible side effects of doxepin (Sinequan)
(Adapin, SINEquan)?
* What is the most important information I should know about
doxepin (Sinequan) (Adapin, SINEquan)?
* What should I discuss with my healthcare provider before taking
doxepin (Sinequan) (Adapin, SINEquan)?
* How should I take doxepin (Sinequan) (Adapin, SINEquan)?
* What happens if I miss a dose (Adapin, SINEquan)?
* What happens if I overdose (Adapin, SINEquan)?
* What should I avoid while taking doxepin (Sinequan) (Adapin,
SINEquan)?
* What other drugs will affect doxepin (Sinequan) (Adapin,
SINEquan)?
* Where can I get more information (Adapin, SINEquan)?
What is doxepin (Sinequan) (Adapin, SINEquan)?
This medication guide provides information about the use of doxepin
(Sinequan or other generic names) to treat depression or anxiety.
Silenor is another brand of doxepin that is not covered in this
medication guide.
Doxepin is a tricyclic antidepressant that affects chemicals in the
brain that may be unbalanced.
Doxepin (Sinequan or other generic name) is used to treat
symptoms of depression and/or anxiety associated with alcoholism,
psychiatric conditions, or manic-depressive conditions.
Doxepin may also be used for purposes not listed in this medication
guide.
What are the possible side effects of doxepin (Sinequan) (Adapin, SINEquan)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Report any new or worsening symptoms to your doctor, such as: mood or
behavior changes, anxiety, panic attacks, trouble sleeping, or if
you feel impulsive, irritable, agitated, hostile, aggressive, restless,
hyperactive (mentally or physically), more depressed, or have thoughts
about suicide or hurting yourself.
Call your doctor at once if you have:
* blurred vision, tunnel vision, eye pain or swelling, seeing
halos around lights;
* a light-headed feeling, like you might pass out;
* skin rash, bruising, severe tingling, numbness, pain, muscle
weakness;
* tremors, restless muscle movements in your eyes, tongue, jaw,
or neck;
* confusion, hallucinations, unusual thoughts, seizure
(convulsions); or
* painful or difficult urination, urinating less than usual.
Common side effects may include:
* drowsiness;
* vision changes;
* nausea, vomiting, diarrhea, indigestion, loss of
appetite;
* dry mouth, mouth sores, taste problems;
* breast swelling (in men or women); or
* decreased or increased sex drive.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about doxepin (Sinequan)
(Adapin, SINEquan)?
You should not take doxepin if you have glaucoma or problems with
urination. Do not use if you are allergic to doxepin or to similar
antidepressants.
Do not use this medicine if you have used an MAO inhibitor in the past
14 days, such as isocarboxazid, linezolid, methylene blue
injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Some young people have thoughts about suicide when first taking an
antidepressant. Stay alert to changes in your mood or symptoms. Report
any new or worsening symptoms to your doctor.
Do not give this medicine to anyone under 18 years old without the
advice of a doctor. Doxepin is not approved for use in children.
Sinequan Patient Information including How Should I Take
Depression Overview:What is Depression?
Understanding Depression Slideshow
RxList
Take the Depression Quiz
Depression:Tips for Exercise Diet and Stress Reduction
Depression Tips Slideshow Pictures
What should I discuss with my healthcare provider before taking doxepin
(Sinequan) (Adapin, SINEquan)?
You should not use doxepin if you are allergic to it, or if you have:
* glaucoma;
* urination problems; or
* an allergy to similar antidepressants such as
amitriptyline, amoxapine, clomipramine,
desipramine, imipramine, nortriptyline, protriptyline, or
trimipramine.
Do not use doxepin if you have used an MAO inhibitor in the past 14
days. A dangerous drug interaction could occur. MAO inhibitors include
isocarboxazid, linezolid, methylene blue injection, phenelzine,
rasagiline, selegiline, tranylcypromine, and others.
To make sure doxepin is safe for you, tell your doctor if you have:
* sleep apnea (breathing stops during sleep);
* diabetes (doxepin may raise or lower blood sugar); or
* bipolar disorder (manic-depression).
Some young people have thoughts about suicide when first taking an
antidepressant. Your doctor will need to check your progress at regular
visits while you are using doxepin. Your family or other caregivers
should also be alert to changes in your mood or symptoms.
It is not known whether this medicine will harm an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant.
It is not known whether doxepin passes into breast milk or if it could
harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Do not give this medicine to anyone under 18 years old without the
advice of a doctor. Doxepin is not approved for use in children.
How should I take doxepin (Sinequan) (Adapin, SINEquan)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose to make sure you get the best results. Do
not take this medicine in larger or smaller amounts or for longer than
recommended.
Measure doxepin oral concentrate (liquid) with the special
dose-measuring dropper provided. Do not use a regular table spoon. If
you do not have a dose-measuring dropper, ask your pharmacist for one.
Empty the measured dose from the medicine dropper into a small glass (4
ounces) of water, milk, orange juice, grapefruit juice, tomato
juice, prune juice, or pineapple juice. Do not use grape juice or a
carbonated soft drink to mix doxepin oral concentrate. Stir the mixture
and drink all of it right away. Do not save it for later use.
Do not stop using doxepin suddenly, or you could have unpleasant
withdrawal symptoms. Ask your doctor how to avoid withdrawal
symptoms when you stop using doxepin.
It may take up to 3 weeks before your symptoms improve. Keep using the
medication as directed and tell your doctor if your symptoms do not
improve.
Store at room temperature away from moisture, heat, and light.
Sinequan Patient Information including If I Miss a Dose
Depression Overview:What is Depression?
Understanding Depression Slideshow
RxList
Take the Depression Quiz
Depression:Tips for Exercise Diet and Stress Reduction
Depression Tips Slideshow Pictures
What happens if I miss a dose (Adapin, SINEquan)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Adapin, SINEquan)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222. An overdose of doxepin can be fatal.
What should I avoid while taking doxepin (Sinequan) (Adapin, SINEquan)?
Do not drink alcohol. Doxepin can increase the effects of alcohol,
which could be dangerous.
Doxepin may impair your thinking or reactions. Be careful if you drive
or do anything that requires you to be alert.
What other drugs will affect doxepin (Sinequan) (Adapin, SINEquan)?
Taking doxepin with other drugs that make you sleepy or slow your
breathing can increase these effects. Ask your doctor before taking
doxepin with a sleeping pill, narcotic pain medicine, muscle
relaxer, or medicine for anxiety, depression, or seizures.
Before taking doxepin, tell your doctor if you have used an "SSRI"
antidepressant in the past 5 weeks, such as citalopram,
escitalopram, fluoxetine, fluvoxamine, paroxetine, or
sertraline.
You must wait at least 5 weeks after stopping fluoxetine (Prozac)
before you can take doxepin.
Other drugs may interact with doxepin, including prescription and
over-the-counter medicines, vitamins, and herbal products. Not all
possible interactions are listed in this medication guide. Tell each of
your health care providers about all medicines you use now and any
medicine you start or stop using.
Where can I get more information (Adapin, SINEquan)?
Your pharmacist can provide more information about doxepin (Sinequan).
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