* Generic Name: olanzapine
* Brand Name: Zyprexa, Zyprexa Zydis
* What is olanzapine (ZyPREXA, ZyPREXA Zydis)?
* What are the possible side effects of olanzapine (ZyPREXA,
ZyPREXA Zydis)?
* What is the most important information I should know about
olanzapine (ZyPREXA, ZyPREXA Zydis)?
* What should I discuss with my healthcare provider before taking
olanzapine (ZyPREXA, ZyPREXA Zydis)?
* How should I take olanzapine (ZyPREXA, ZyPREXA Zydis)?
* What happens if I miss a dose (ZyPREXA, ZyPREXA Zydis)?
* What happens if I overdose (ZyPREXA, ZyPREXA Zydis)?
* What should I avoid while taking olanzapine (ZyPREXA, ZyPREXA
Zydis)?
* What other drugs will affect olanzapine (ZyPREXA, ZyPREXA
Zydis)?
* Where can I get more information (ZyPREXA, ZyPREXA Zydis)?
What is olanzapine (ZyPREXA, ZyPREXA Zydis)?
Olanzapine is an antipsychotic medication that affects
chemicals in the brain.
Olanzapine is used to treat the symptoms of psychotic conditions such
as schizophrenia and bipolar disorder (manic depression) in
adults and children who are at least 13 years old. Olanzapine is
sometimes used together with other antipsychotic medications or
antidepressants.
Olanzapine may also be used for purposes not listed in this medication
guide.
What are the possible side effects of olanzapine (ZyPREXA, ZyPREXA Zydis)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Seek medical treatment if you have symptoms of a serious drug reaction
that can affect many parts of your body. Symptoms may include: skin
rash, fever, swollen glands, flu-like symptoms, unusual bruising, or
jaundice (yellowing of your skin or eyes).
Call your doctor at once if you have:
* uncontrolled muscle movements in your face (chewing, lip smacking,
frowning, tongue movement, blinking or eye movement);
* trouble speaking or swallowing;
* swelling in your hands or feet;
* confusion, unusual thoughts or behavior, hallucinations, or
thoughts about hurting yourself;
* sudden weakness or ill feeling, fever, chills, sore throat,
swollen gums, painful mouth sores, pain when swallowing, skin
sores, cold or flu symptoms, cough;
* signs of dehydration--feeling very thirsty or hot, being unable to
urinate, heavy sweating, or hot and dry skin;
* liver problems--upper stomach pain, itching, loss of appetite,
dark urine, clay-colored stools, jaundice (yellowing of the
skin or eyes);
* high blood sugar--increased thirst, increased urination,
hunger, dry mouth, fruity breath odor, drowsiness, dry skin,
blurred vision, weight loss; or
* severe nervous system reaction--very stiff (rigid) muscles, high
fever, sweating, confusion, fast or uneven heartbeats, tremors,
feeling like you might pass out.
Common side effects may include:
* weight gain (more likely in teenagers), increased appetite;
* headache, dizziness, drowsiness, feeling tired or restless;
* problems with speech or memory;
* tremors or shaking, numbness or tingly feeling;
* changes in personality;
* dry mouth, or increased salivation;
* stomach pain, constipation; or
* pain in your arms or legs.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about olanzapine
(ZyPREXA, ZyPREXA Zydis)?
Olanzapine is not approved for use in psychotic conditions related to
dementia. Olanzapine may increase the risk of death in older adults
with dementia-related conditions.
Zyprexa Patient Information including How Should I Take
Schizophrenia: Types, Causes, Symptoms, and Treatment
Schizophrenia Slideshow Pictures
RxList
Take the Schizophrenia Quiz
What should I discuss with my healthcare provider before taking olanzapine
(ZyPREXA, ZyPREXA Zydis)?
Olanzapine is not approved for use in psychotic conditions related to
dementia. Olanzapine may increase the risk of death in older adults
with dementia-related conditions.
You should not take olanzapine if you are allergic to it.
Long-term use of olanzapine can cause a serious movement disorder that
may not be reversible. Symptoms include uncontrollable muscle movements
of your lips, tongue, eyes, face, arms, or legs. The longer you take
olanzapine, the more likely you are to develop this movement disorder.
The risk of this side effect is higher in women and older adults.
To make sure olanzapine is safe for you, tell your doctor if you have
ever had:
* liver disease;
* heart disease, high or low blood pressure;
* low white blood cell (WBC) counts;
* high cholesterol or triglycerides;
* heart failure, heart attack, or stroke;
* breast cancer;
* seizures or epilepsy;
* diabetes;
* an enlarged prostate or difficulty urinating;
* bowel problems; or
* narrow-angle glaucoma.
Tell your doctor if you are pregnant or plan to become pregnant while
using this medication.
Taking antipsychotic medication during the last 3 months of pregnancy
may cause problems in the newborn, such as withdrawal symptoms,
breathing problems, feeding problems, fussiness, tremors, and limp or
stiff muscles. However, you may have withdrawal symptoms or other
problems if you stop taking your medicine during pregnancy. If you
become pregnant while taking olanzapine, do not stop taking it without
your doctor's advice.
Olanzapine can pass into breast milk and may harm a nursing baby. You
should not breast-feed while using olanzapine.
The olanzapine orally disintegrating tablet (Zyprexa Zydis) may
contain phenylalanine. Talk to your doctor before using this form
of olanzapine if you have phenylketonuria (PKU).
How should I take olanzapine (ZyPREXA, ZyPREXA Zydis)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose to make sure you get the best results. Do
not take this medicine in larger or smaller amounts or for longer than
recommended.
Olanzapine can be taken with or without food.
Olanzapine is usually taken once a day. Olanzapine may be only part of
a complete program of treatment that also includes counseling and other
psychological support programs. Follow your doctor's instructions.
To take olanzapine orally disintegrating tablet (Zyprexa Zydis):
* Keep the tablet in its original container until you are ready to
take it.
* Using dry hands, place the tablet in your mouth. It will begin to
dissolve right away.
* Do not swallow the tablet whole. Allow it to dissolve in your mouth
without chewing.
* Swallow several times as the tablet dissolves. If desired, you may
drink liquid to help swallow the dissolved tablet.
Call your doctor if your symptoms do not improve, or if they get worse
while using olanzapine.
Do not stop using olanzapine suddenly, even if you feel fine. Stopping
suddenly may cause serious side effects.
Olanzapine can cause high blood sugar (hyperglycemia). If you
are diabetic, check your blood sugar levels on a regular basis while
you are taking olanzapine.
You may gain weight or have high cholesterol and triglycerides (types
of fat) while taking this medicine, especially if you are a teenager.
Your blood may need to be tested often. Visit your doctor regularly.
If you are taking a combination of drugs, use all medications as
directed by your doctor. Read the medication guide or patient
instructions provided with each medication. Do not change your doses or
medication schedule without your doctor's advice.
Store at room temperature away from moisture, heat, and light.
Zyprexa Patient Information including If I Miss a Dose
Schizophrenia: Types, Causes, Symptoms, and Treatment
Schizophrenia Slideshow Pictures
RxList
Take the Schizophrenia Quiz
What happens if I miss a dose (ZyPREXA, ZyPREXA Zydis)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (ZyPREXA, ZyPREXA Zydis)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
Overdose symptoms may include drowsiness, agitation, aggression,
slurred speech, confusion, increased heart rate, jerky or uncontrolled
muscle movements, trouble breathing, or fainting.
What should I avoid while taking olanzapine (ZyPREXA, ZyPREXA Zydis)?
Olanzapine may impair your thinking or reactions. Be careful if you
drive or do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may
feel dizzy. Dizziness or severe drowsiness can cause falls, fractures,
or other injuries.
Avoid drinking alcohol. Dangerous side effects could occur.
Avoid becoming overheated or dehydrated. Drink plenty of fluids,
especially in hot weather and during exercise. It is easier to
become dangerously overheated and dehydrated while you are taking
olanzapine.
What other drugs will affect olanzapine (ZyPREXA, ZyPREXA Zydis)?
Taking olanzapine with other drugs that make you sleepy or slow your
breathing can cause dangerous or life-threatening side effects. Ask
your doctor before taking a sleeping pill, narcotic pain medicine,
prescription cough medicine, a muscle relaxer, or medicine for anxiety,
depression, or seizures.
Other drugs may interact with olanzapine, including prescription and
over-the-counter medicines, vitamins, and herbal products. Tell your
doctor about all your current medicines and any medicine you start or
stop using.
Where can I get more information (ZyPREXA, ZyPREXA Zydis)?
Your pharmacist can provide more information about olanzapine.
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