* Generic Name: propranolol
* Brand Name: Inderal
* What is propranolol?
* What are the possible side effects of propranolol?
* What is the most important information I should know about
propranolol?
* What should I discuss with my healthcare provider before taking
propranolol?
* How should I take propranolol?
* What happens if I miss a dose?
* What happens if I overdose?
* What should I avoid while taking propranolol?
* What other drugs will affect propranolol?
* Where can I get more information?
What is propranolol?
Propranolol is a beta-blocker. Beta-blockers affect the heart and
circulation (blood flow through arteries and veins).
Propranolol is used to treat tremors, angina (chest pain),
hypertension (high blood pressure), heart rhythm disorders,
and other heart or circulatory conditions. It is also used to treat
or prevent heart attack, and to reduce the severity and frequency
of migraine headaches.
Hemangeol (propranolol oral liquid 4.28 milligrams) is given to infants
who are at least 5 weeks old to treat a genetic condition called
infantile hemangiomas. Hemangiomas are caused by blood vessels grouping
together in an abnormal way. These blood vessels form benign
(non-cancerous) growths that can develop into ulcers or red marks on
the skin. Hemangiomas can also cause more serious complications inside
the body (in the liver, brain, or digestive system).
Propranolol may also be used for purposes not listed in this medication
guide.
What are the possible side effects of propranolol?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficult breathing; swelling of your face, lips, tongue, or
throat.
Call your doctor at once if you have:
* slow or uneven heartbeats;
* a light-headed feeling, like you might pass out;
* wheezing or trouble breathing;
* shortness of breath (even with mild exertion), swelling, rapid
weight gain;
* sudden weakness, vision problems, or loss of coordination
(especially in a child with hemangioma that affects the face or
head);
* cold feeling in your hands and feet;
* depression, confusion, hallucinations;
* liver problems--nausea, upper stomach pain, itching, tired feeling,
loss of appetite, dark urine, clay-colored stools,
jaundice (yellowing of the skin or eyes);
* low blood sugar--headache, hunger, weakness, sweating, confusion,
irritability, dizziness, fast heart rate, or feeling jittery;
* low blood sugar in a baby--pale skin, blue or purple skin,
sweating, fussiness, crying, not wanting to eat, feeling cold,
drowsiness, weak or shallow breathing (breathing may stop for short
periods), seizure (convulsions), or loss of consciousness; or
* severe skin reaction--fever, sore throat, swelling in your face
or tongue, burning in your eyes, skin pain, followed by a red or
purple skin rash that spreads (especially in the face or upper
body) and causes blistering and peeling.
Common side effects may include:
* nausea, vomiting, diarrhea, constipation, stomach cramps;
* decreased sex drive, impotence, or difficulty having an
orgasm;
* sleep problems (insomnia); or
* tired feeling.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about propranolol?
You should not use this medicine if you have asthma, very slow
heart beats, or a serious heart condition such as "sick sinus
syndrome" or "AV block" (unless you have a pacemaker).
Babies who weigh less than 4.5 pounds should not be given Hemangeol
oral liquid.
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What should I discuss with my healthcare provider before taking propranolol?
You should not use propranolol if you are allergic to it, or if you
have:
* asthma;
* very slow heart beats that have caused you to faint; or
* a serious heart condition such as "sick sinus syndrome" or "AV
block" (unless you have a pacemaker).
Babies who weigh less than 4.5 pounds should not be given Hemangeol
oral liquid.
To make sure propranolol is safe for you, tell your doctor if you have:
* a muscle disorder;
* bronchitis, emphysema, or other breathing disorders;
* low blood sugar, or diabetes (propranolol can make it harder
for you to tell when you have low blood sugar);
* slow heartbeats, low blood pressure;
* congestive heart failure;
* depression;
* liver or kidney disease;
* a thyroid disorder;
* pheochromocytoma (tumor of the adrenal gland); or
* problems with circulation (such as Raynaud's syndrome).
It is not known whether propranolol will harm an unborn baby. Tell your
doctor if you are pregnant or plan to become pregnant while using this
medicine.
Propranolol can pass into breast milk and may harm a nursing baby. Tell
your doctor if you are breast-feeding a baby.
How should I take propranolol?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose to make sure you get the best results. Do
not take this medicine in larger or smaller amounts or for longer than
recommended.
Adults may take propranolol with or without food, but take it the same
way each time.
Take this medicine at the same time each day.
Do not crush, chew, break, or open an extended-release capsule. Swallow
it whole.
Hemangeol must be given to an infant during or just after a feeding.
Doses should be spaced at least 9 hours apart. Make sure your child
gets fed regularly while taking this medicine. Tell your doctor when
the child has any changes in weight. Hemangeol doses are based on
weight in children, and any changes may affect your child's dose.
Call your doctor if a child taking Hemangeol is sick with vomiting, or
has any loss of appetite.
Measure liquid medicine with the dosing syringe provided, or with a
special dose-measuring spoon or medicine cup. If you do not have a
dose-measuring device, ask your pharmacist for one.
Do not shake Hemangeol liquid.
Your blood pressure will need to be checked often.
If you need surgery, tell the surgeon ahead of time that you are
using propranolol. You may need to stop using the medicine for a short
time.
Do not skip doses or stop using propranolol suddenly. Stopping suddenly
may make your condition worse. Follow your doctor's instructions about
tapering your dose.
This medicine can cause unusual results with certain medical tests.
Tell any doctor who treats you that you are using propranolol.
If you are being treated for high blood pressure, keep using this
medicine even if you feel well. High blood pressure often has no
symptoms. You may need to use blood pressure medicine for the rest of
your life.
Propranolol is only part of a complete program of treatment for
hypertension that may also include diet, exercise, and weight
control. Follow your diet, medication, and exercise routines very
closely if you are being treated for hypertension.
Store at room temperature away from moisture and heat. Do not allow
liquid medicine to freeze. Throw away any unused Hemangeol 2 months
after you first opened the bottle.
Inderal Patient Information including If I Miss a Dose
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High Blood Pressure Slideshow Pictures
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What happens if I miss a dose?
For regular (short-acting) propranolol: Take the missed dose as soon as
you remember. Skip the missed dose if your next dose is less than 4
hours away.
For extended-release propranolol (Inderal LA, InnoPran XL and others):
Take the missed dose as soon as you remember. Skip the missed dose if
your next dose is less than 8 hours away.
Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
Overdose symptoms may include slow or uneven heartbeats, dizziness,
weakness, or fainting.
What should I avoid while taking propranolol?
Avoid drinking alcohol. It may increase your blood levels of
propranolol.
Avoid getting up too fast from a sitting or lying position, or you may
feel dizzy. Get up slowly and steady yourself to prevent a fall.
What other drugs will affect propranolol?
Tell your doctor about all medicines you use, and those you start or
stop using during your treatment with propranolol, especially:
* a blood thinner--warfarin, Coumadin, Jantoven;
* an antidepressant--amitriptyline, clomipramine,
desipramine, imipramine, and others;
* drugs to treat high blood pressure or a prostate
disorder--doxazosin, prazosin, terazosin;
* heart or blood pressure medicine--amiodarone, diltiazem,
propafenone, quinidine, verapamil, and others;
* NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen
(Advil, Motrin), naproxen (Aleve), celecoxib,
diclofenac, indomethacin, meloxicam, and others; or
* steroid medicine--prednisone and others.
This list is not complete. Other drugs may interact with propranolol,
including prescription and over-the-counter medicines, vitamins, and
herbal products. Not all possible interactions are listed in this
medication guide.
Where can I get more information?
Your pharmacist can provide more information about propranolol.
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