* Generic Name: hydroxychloroquine
* Brand Name: Plaquenil
* What is hydroxychloroquine (Plaquenil, Plaquenil Sulfate,
Quineprox)?
* What are the possible side effects of hydroxychloroquine
(Plaquenil, Plaquenil Sulfate, Quineprox)?
* What is the most important information I should know about
hydroxychloroquine (Plaquenil, Plaquenil Sulfate, Quineprox)?
* What should I discuss with my health care provider before
taking hydroxychloroquine (Plaquenil, Plaquenil Sulfate,
Quineprox)?
* How should I take hydroxychloroquine (Plaquenil, Plaquenil
Sulfate, Quineprox)?
* What happens if I miss a dose (Plaquenil, Plaquenil Sulfate,
Quineprox)?
* What happens if I overdose (Plaquenil, Plaquenil Sulfate,
Quineprox)?
* What should I avoid while taking hydroxychloroquine (Plaquenil,
Plaquenil Sulfate, Quineprox)?
* What other drugs will affect hydroxychloroquine (Plaquenil,
Plaquenil Sulfate, Quineprox)?
* Where can I get more information (Plaquenil, Plaquenil Sulfate,
Quineprox)?
What is hydroxychloroquine (Plaquenil, Plaquenil Sulfate, Quineprox)?
Hydroxychloroquine is used to treat or prevent malaria, a disease
caused by parasites that enter the body through the bite of a mosquito.
Malaria is common in areas such as Africa, South America, and Southern
Asia. This medicine is not effective against all strains of malaria.
Hydroxychloroquine is also used to treat symptoms of rheumatoid
arthritis and discoid or systemic lupus erythematosus.
Hydroxychloroquine may also be used for purposes not listed in this
medication guide.
What are the possible side effects of hydroxychloroquine (Plaquenil,
Plaquenil Sulfate, Quineprox)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Taking hydroxychloroquine long-term or at high doses may cause
irreversible damage to the retina of your eye. Stop taking
hydroxychloroquine and call your doctor at once if you have trouble
focusing, if you see light streaks or flashes in your vision, or if you
notice any swelling or color changes in your eyes.
Call your doctor at once if you have:
* headache with chest pain and severe dizziness, fainting, fast
or pounding heartbeats;
* very slow heart rate, weak pulse;
* muscle weakness, numbness or tingling;
* low blood sugar--headache, hunger, sweating, irritability,
dizziness, nausea, fast heart rate, and feeling anxious or shaky;
or
* low blood cell counts--fever, chills, sore throat, weakness or
ill feeling, swollen gums, mouth sores, skin sores, rapid heart
rate, pale skin, easy bruising, unusual bleeding, feeling
light-headed.
Common side effects may include:
* headache, dizziness, ringing in your ears;
* nausea, vomiting, stomach pain;
* loss of appetite, weight loss;
* mood changes, feeling nervous or irritable;
* skin rash or itching; or
* hair loss.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about hydroxychloroquine
(Plaquenil, Plaquenil Sulfate, Quineprox)?
Taking hydroxychloroquine long-term or at high doses may cause
irreversible damage to the retina of your eye. Stop taking
hydroxychloroquine and call your doctor at once if you have trouble
focusing, if you see light streaks or flashes in your vision, or if you
notice any swelling or color changes in your eyes.
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What should I discuss with my health care provider before taking
hydroxychloroquine (Plaquenil, Plaquenil Sulfate, Quineprox)?
You should not use hydroxychloroquine if you are allergic to it.
Hydroxychloroquine should not be used for long-term treatment in
children.
To make sure hydroxychloroquine is safe for you, tell your doctor if
you have:
* a history of vision changes or damage to your retina caused by an
anti-malaria medication;
* heart disease, heart rhythm disorder (such as long QT
syndrome);
* diabetes;
* a stomach disorder;
* an allergy to quinine;
* liver or kidney disease;
* psoriasis;
* alcoholism; or
* a genetic enzyme disorder such as porphyria or
glucose-6-phosphate dehydrogenase (G6PD) deficiency.
It is not known whether this medicine will harm an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant.
Malaria is more likely to cause death in a pregnant woman. If you are
pregnant, talk with your doctor about the risks of traveling to areas
where malaria is common.
It is not known whether hydroxychloroquine passes into breast milk or
if it could harm a nursing baby. Tell your doctor if you are
breast-feeding a baby.
Hydroxychloroquine is not approved for use by anyone younger than 18
years old.
How should I take hydroxychloroquine (Plaquenil, Plaquenil Sulfate,
Quineprox)?
Follow all directions on your prescription label. Do not take this
medicine in larger or smaller amounts or for longer than recommended.
Hydroxychloroquine is sometimes given only once per week. Choose the
same day each week to take this medicine if you are on a weekly dosing
schedule.
Take hydroxychloroquine with a meal or a glass of milk.
To prevent malaria: Start taking the medicine 2 weeks before entering
an area where malaria is common. Continue taking the medicine regularly
during your stay and for at least 8 weeks after you leave the area.
To treat malaria: Hydroxychloroquine is usually given for 3 days,
starting with one high dose followed by a smaller dose during the next
2 days in a row.
Take this medicine for the full prescribed length of time for malaria.
Your symptoms may improve before the infection is completely cleared.
Use protective clothing, insect repellents, and mosquito netting around
your bed to further prevent mosquito bites that could cause malaria.
Call your doctor as soon as possible if you have been exposed to
malaria, or if you have fever or other symptoms of illness during or
after a stay in an area where malaria is common.
No medication is 100% effective in treating or preventing all types of
malaria. For best results, keep using the medication as directed. Talk
with your doctor if you have fever, vomiting, or diarrhea during your
treatment.
When treating lupus or arthritis, hydroxychloroquine is usually given
daily for several weeks or months. For best results, keep using the
medication as directed. Talk with your doctor if your symptoms do not
improve after 6 months of treatment.
While using hydroxychloroquine, you may need frequent blood tests and
vision exams.
Store at room temperature away from moisture, heat, and light.
Plaquenil Patient Information including If I Miss a Dose
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What happens if I miss a dose (Plaquenil, Plaquenil Sulfate, Quineprox)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Plaquenil, Plaquenil Sulfate, Quineprox)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222. An overdose of hydroxychloroquine can be fatal,
especially in children.
Hydroxychloroquine overdose must be treated quickly. You may be told to
induce vomiting right away (at home, before transport to an emergency
room). Ask the poison control center how to induce vomiting in the case
of an overdose.
Overdose symptoms may include drowsiness, vision changes, slow heart
rate, chest pain, severe dizziness, seizure (convulsions), or
shallow breathing.
What should I avoid while taking hydroxychloroquine (Plaquenil, Plaquenil
Sulfate, Quineprox)?
Avoid taking an antacid or Kaopectate (kaolin-pectin) within 4
hours before or after you take hydroxychloroquine. Some antacids
can make it harder for your body to absorb hydroxychloroquine.
What other drugs will affect hydroxychloroquine (Plaquenil, Plaquenil
Sulfate, Quineprox)?
Hydroxychloroquine can cause serious liver or heart problems,
especially if you use certain medicines at the same time, including:
* other medicines to treat malaria;
* an antibiotic or antifungal medicine;
* antiviral medicine to treat hepatitis or HIV/AIDS;
* antidepressants or antipsychotic medicines;
* birth control pills or hormone replacement therapy;
* cancer medication;
* cholesterol-lowering medication;
* heart or blood pressure medicine;
* pain or arthritis medicines (including aspirin, Tylenol,
Advil, and Aleve);
* seizure medication;
* stomach acid reducers; or
* tuberculosis medicine.
This list is not complete and many other drugs can interact with
hydroxychloroquine. This includes prescription and over-the-counter
medicines, vitamins, and herbal products. Not all possible interactions
are listed in this medication guide. Tell your doctor about all
medicines you use, and those you start or stop using during your
treatment with hydroxychloroquine. Give a list of all your medicines to
any healthcare provider who treats you.
Where can I get more information (Plaquenil, Plaquenil Sulfate, Quineprox)?
Your pharmacist can provide more information about hydroxychloroquine.
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