* Generic Name: promethazine
* Brand Name: Phenergan
* What is promethazine (Pentazine, Phenergan, Promacot)?
* What are the possible side effects of promethazine (Pentazine,
Phenergan, Promacot)?
* What is the most important information I should know about
promethazine (Pentazine, Phenergan, Promacot)?
* What should I discuss with my healthcare provider before taking
promethazine (Pentazine, Phenergan, Promacot)?
* How should I take promethazine (Pentazine, Phenergan,
Promacot)?
* What happens if I miss a dose (Pentazine, Phenergan, Promacot)?
* What happens if I overdose (Pentazine, Phenergan, Promacot)?
* What should I avoid while taking promethazine (Pentazine,
Phenergan, Promacot)?
* What other drugs will affect promethazine (Pentazine,
Phenergan, Promacot)?
* Where can I get more information (Pentazine, Phenergan,
Promacot)?
What is promethazine (Pentazine, Phenergan, Promacot)?
Promethazine is in a group of drugs called phenothiazines
(FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals
in your brain. Promethazine also acts as an antihistamine. It blocks
the effects of the naturally occurring chemical histamine in your
body.
Promethazine is used to treat allergy symptoms such as itching,
runny nose, sneezing, itchy or watery eyes, hives, and itchy
skin rashes.
Promethazine also prevents motion sickness, and treats nausea
and vomiting or pain after surgery. It is also used as a sedative
or sleep aid.
Promethazine is not for use in treating symptoms of asthma,
pneumonia, or other lower respiratory tract infections.
Promethazine may also be used for purposes not listed in this
medication guide.
What are the possible side effects of promethazine (Pentazine, Phenergan,
Promacot)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficult breathing; swelling of your face, lips, tongue, or
throat.
Stop using promethazine and call your doctor at once if you have:
* severe drowsiness, weak or shallow breathing;
* a light-headed feeling, like you might pass out;
* confusion, agitation, hallucinations, nightmares;
* seizure (convulsions);
* fast or slow heartbeats;
* jaundice (yellowing of the skin or eyes);
* uncontrolled muscle movements in your face (chewing, lip smacking,
frowning, tongue movement, blinking or eye movement);
* easy bruising or bleeding (nosebleeds, bleeding gums);
* sudden weakness or ill feeling, fever, chills, sore throat,
mouth sores, red or swollen gums, trouble swallowing; or
* severe nervous system reaction--very stiff (rigid) muscles, high
fever, sweating, confusion, fast or uneven heartbeats, tremors,
feeling like you might pass out.
Side effects such as confusion and severe drowsiness may be more likely
in older adults.
Common side effects may include:
* drowsiness, dizziness;
* ringing in your ears;
* double vision;
* feeling nervous;
* dry mouth; or
* tired feeling, sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about promethazine
(Pentazine, Phenergan, Promacot)?
Promethazine should not be given to a child younger than 2 years old.
Promethazine can cause severe breathing problems or death in very young
children.
Phenergan Patient Information including How Should I Take
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What should I discuss with my healthcare provider before taking promethazine
(Pentazine, Phenergan, Promacot)?
Promethazine should not be given to a child younger than 2 years old.
Promethazine can cause severe breathing problems or death in very young
children. Carefully follow your doctor's instructions when giving this
medicine to a child of any age.
You should not take this medicine if you are allergic to promethazine
or to similar medicines such as chlorpromazine, fluphenazine,
mesoridazine, perphenazine, prochlorperazine, thioridazine, or
trifluperazine.
To make sure promethazine is safe for you, tell your doctor if you
have:
* asthma, chronic obstructive pulmonary disease (COPD),
sleep apnea, or other breathing disorder;
* a sulfite allergy;
* a history of seizures;
* a weak immune system (bone marrow depression);
* glaucoma;
* enlarged prostate or problems with urination;
* stomach ulcer or obstruction;
* heart disease or high blood pressure;
* liver disease;
* adrenal gland tumor (pheochromocytoma);
* low levels of calcium in your blood (hypocalcemia); or
* if you have ever had a serious side effect while using promethazine
or any other phenothiazine.
It is not known whether promethazine will harm an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant while using
this medicine.
It is not known whether promethazine passes into breast milk or if it
could harm a nursing baby. You should not breast-feed while using this
medicine.
How should I take promethazine (Pentazine, Phenergan, Promacot)?
Follow all directions on your prescription label. Your doctor may
occasionally change your dose to make sure you get the best results. Do
not take this medicine in larger or smaller amounts or for longer than
recommended.
Promethazine is often taken at bedtime or before meals. For motion
sickness, promethazine is usually started within 1 hour before
traveling. When used for surgery, promethazine is usually taken the
night before the surgery.
How often you take this medicine and the timing of your dose will
depend on the condition being treated.
Measure liquid medicine with the dosing syringe provided, or with a
special dose-measuring spoon or medicine cup. If you do not have a
dose-measuring device, ask your pharmacist for one.
If a child is using this medicine, tell your doctor if the child has
any changes in weight. Promethazine doses are based on weight in
children, and any changes may affect your child's dose.
Call your doctor if your symptoms do not improve, or if they get worse
while using promethazine.
This medicine can cause unusual results with certain medical tests.
Tell any doctor who treats you that you are using promethazine.
Store at room temperature away from moisture, heat, and light.
Phenergan Patient Information including If I Miss a Dose
Could I Be Allergic? Discover Your Allergy Triggers
Common Allergy Triggers Slideshow Pictures
RxList
Take the Quiz on Allergies
Nasal Allergy Relief:Products That Work
Nasal Allergy Relief Products Slideshow Pictures
What happens if I miss a dose (Pentazine, Phenergan, Promacot)?
Take the missed dose as soon as you remember. Skip the missed dose if
it is almost time for your next scheduled dose. Do not take extra
medicine to make up the missed dose.
What happens if I overdose (Pentazine, Phenergan, Promacot)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
Overdose symptoms may include overactive reflexes, loss of
coordination, severe drowsiness or weakness, fainting, dilated
pupils, weak or shallow breathing, or seizure (convulsions).
What should I avoid while taking promethazine (Pentazine, Phenergan,
Promacot)?
This medicine may impair your thinking or reactions. Be careful if you
drive or do anything that requires you to be alert. Avoid getting up
too fast from a sitting or lying position, or you may feel dizzy. Get
up slowly and steady yourself to prevent a fall.
Drinking alcohol can increase certain side effects of promethazine.
Avoid exposure to sunlight or tanning beds. Promethazine can make you
sunburn more easily. Wear protective clothing and use sunscreen
(SPF 30 or higher) when you are outdoors.
What other drugs will affect promethazine (Pentazine, Phenergan, Promacot)?
Using this medicine with other drugs that make you sleepy or slow your
breathing can cause dangerous or life-threatening side effects. Ask
your doctor before taking promethazine with a sleeping pill,
narcotic pain medicine, muscle relaxer, or medicine for anxiety,
depression, or seizures.
Other drugs may interact with promethazine, including prescription and
over-the-counter medicines, vitamins, and herbal products. Tell each of
your health care providers about all medicines you use now and any
medicine you start or stop using.
Where can I get more information (Pentazine, Phenergan, Promacot)?
Your pharmacist can provide more information about promethazine.
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