* Generic Name: sildenafil citrate
* Brand Name: Revatio
* What is sildenafil (Revatio, Viagra)?
* What are the possible side effects of oral sildenafil (Revatio,
Viagra)?
* What is the most important information I should know about oral
sildenafil (Revatio, Viagra)?
* What should I discuss with my healthcare provider before taking
oral sildenafil (Revatio, Viagra)?
* How should I take oral sildenafil (Revatio, Viagra)?
* What happens if I miss a dose (Revatio, Viagra)?
* What happens if I overdose (Revatio, Viagra)?
* What should I avoid while taking oral sildenafil (Revatio,
Viagra)?
* What other drugs will affect oral sildenafil (Revatio, Viagra)?
* Where can I get more information (Revatio, Viagra)?
What is sildenafil (Revatio, Viagra)?
Sildenafil relaxes muscles of the blood vessels and increases blood
flow to particular areas of the body.
Sildenafil under the name Viagra is used to treat erectile
dysfunction (impotence) in men. Another brand of sildenafil is
Revatio, which is used to treat pulmonary arterial hypertension and
improve exercise capacity in men and women.
Do not take Viagra while also taking Revatio, unless your doctor tells
you to.
Sildenafil may also be used for purposes not listed in this medication
guide.
What are the possible side effects of oral sildenafil (Revatio, Viagra)?
Get emergency medical help if you have signs of an allergic reaction:
hives; difficulty breathing; swelling of your face, lips, tongue, or
throat.
Stop taking sildenafil and get emergency medical help if you have:
* heart attack symptoms--chest pain or pressure, pain spreading to
your jaw or shoulder, nausea, sweating;
* vision changes or sudden vision loss; or
* erection is painful or lasts longer than 4 hours (prolonged
erection can damage the penis).
Call your doctor at once if you have:
* ringing in your ears, or sudden hearing loss;
* irregular heartbeat;
* swelling in your hands, ankles, or feet;
* shortness of breath;
* seizure (convulsions); or
* a light-headed feeling, like you might pass out.
Common side effects may include:
* flushing (warmth, redness, or tingly feeling);
* headache, dizziness;
* abnormal vision (blurred vision, changes in color vision)
* runny or stuffy nose, nosebleeds;
* sleep problems (insomnia);
* muscle pain, back pain; or
* upset stomach.
This is not a complete list of side effects and others may occur. Call
your doctor for medical advice about side effects. You may report side
effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about oral sildenafil
(Revatio, Viagra)?
Some medicines can cause unwanted or dangerous effects when used with
sildenafil. Tell your doctor about all your current medicines,
especially riociguat (Adempas).
Do not take sildenafil if you are also using a nitrate drug for chest
pain or heart problems, including nitroglycerin, isosorbide dinitrate,
isosorbide mononitrate, and some recreational drugs such as
"poppers". Taking sildenafil with a nitrate medicine can cause a sudden
and serious decrease in blood pressure.
Contact your doctor or seek emergency medical attention if your
erection is painful or lasts longer than 4 hours. A prolonged erection
(priapism) can damage the penis.
Stop using sildenafil and get emergency medical help if you have sudden
vision loss.
Revatio Patient Information including How Should I Take
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What should I discuss with my healthcare provider before taking oral
sildenafil (Revatio, Viagra)?
You should not use sildenafil if you are allergic to it, or:
* if you take other medicines to treat pulmonary arterial
hypertension, such as riociguat (Adempas).
Do not take sildenafil if you are also using a nitrate drug for chest
pain or heart problems. This includes nitroglycerin, isosorbide
dinitrate, and isosorbide mononitrate. Nitrates are also found in some
recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking
sildenafil with a nitrate medicine can cause a sudden and serious
decrease in blood pressure.
To make sure sildenafil is safe for you, tell your doctor if you have
ever had:
* heart disease or heart rhythm problems, coronary artery
disease;
* heart attack, stroke, or congestive heart failure;
* high or low blood pressure;
* liver or kidney disease;
* a blood cell disorder such as sickle cell anemia, multiple
myeloma, or leukemia;
* a bleeding disorder such as hemophilia;
* a stomach ulcer;
* retinitis pigmentosa (an inherited condition of the eye);
* a physical deformity of the penis (such as Peyronie's disease);
or
* if you have been told you should not have sexual intercourse for
health reasons.
Sildenafil can decrease blood flow to the optic nerve of the eye,
causing sudden vision loss. This has occurred in a small number of
people taking sildenafil, most of whom also had heart disease,
diabetes, high blood pressure, high cholesterol, or certain
pre-existing eye problems, and in those who smoked or were over 50
years old. It is not clear whether sildenafil is the actual cause of
vision loss.
This medicine is not expected to harm an unborn baby. Tell your doctor
if you are pregnant or plan to become pregnant.
It is not known whether sildenafil passes into breast milk or if it
could harm a nursing baby. Tell your doctor if you are breast-feeding a
baby.
Do not give this medication to anyone under 18 years old without
medical advice.
How should I take oral sildenafil (Revatio, Viagra)?
Follow all directions on your prescription label. Do not take this
medicine in larger or smaller amounts or for longer than recommended.
Revatio is usually taken three times each day, about 4 to 6 hours
apart.
Viagra is usually taken only when needed, 30 minutes to 1 hour before
sexual activity. You may take it up to 4 hours before sexual activity.
Do not take Viagra more than once per day.
Shake the oral suspension (liquid) well just before you measure a dose.
Measure liquid medicine with the dosing syringe provided, or with a
special dose-measuring spoon or medicine cup. If you do not have a
dose-measuring device, ask your pharmacist for one.
Viagra can help you have an erection when sexual stimulation occurs. An
erection will not occur just by taking a pill. Follow your doctor's
instructions.
During sexual activity, if you become dizzy or nauseated, or have pain,
numbness, or tingling in your chest, arms, neck, or jaw, stop and call
your doctor right away. You could be having a serious side effect of
sildenafil.
Store at room temperature away from moisture and heat.
Revatio Patient Information including If I Miss a Dose
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What happens if I miss a dose (Revatio, Viagra)?
Since Viagra is used as needed, you are not likely to miss a dose.
If you miss a dose of Revatio, take the missed dose as soon as you
remember. Skip the missed dose if it is almost time for your next
scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Revatio, Viagra)?
Seek emergency medical attention or call the Poison Help line at
1-800-222-1222.
What should I avoid while taking oral sildenafil (Revatio, Viagra)?
Drinking alcohol with this medicine can cause side effects.
Grapefruit and grapefruit juice may interact with sildenafil and
lead to unwanted side effects. Avoid the use of grapefruit products
while taking sildenafil.
Avoid using any other medicines to treat impotence, such as alprostadil
or yohimbine, without first talking to your doctor.
What other drugs will affect oral sildenafil (Revatio, Viagra)?
Do not take sildenafil with similar medications such as avanafil
(Stendra), tadalafil (Cialis) or vardenafil
(Levitra). Tell your doctor about all other medications you use for
erectile dysfunction.
Tell your doctor about all your current medicines and any you start or
stop using, especially:
* drugs to treat high blood pressure or a prostate disorder;
* an antibiotic--clarithromycin, erythromycin, or
telithromycin;
* antifungal medicine--ketoconazole or itraconazole; or
* medicine to treat HIV/AIDS--atazanavir, indinavir, ritonavir, or
saquinavir.
This list is not complete. Other drugs may interact with sildenafil,
including prescription and over-the-counter medicines, vitamins, and
herbal products. Not all possible interactions are listed in this
medication guide.
Where can I get more information (Revatio, Viagra)?
Your pharmacist can provide more information about sildenafil.
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